What Is Platelet-Rich Fibrin (PRF), and How Is It Related to the Platelet-Rich Plasma (PRP) Treatment at Eskulap Clinic in London?

Fibrin, like plasma, is a mesotherapy treatment that uses natural regenerative mechanisms of the patient’s body. However, an additional advantage of fibrin is the possibility of using it for modelling and volumetry of the face. Platelet-rich fibrin treatment, or simply PRF treatment, is used under the eyes, on the face, neck, hands, and neckline. It’s also an excellent alternative to hyaluronic acid and dermal fillers. It supports the production of stem cells and activates fibroblasts to produce new collagen.

At Eskulap Clinic in London and Birmingham, the use of PRF fibrin gives excellent results, not only in reducing skin laxity of lower eyelids but also in the reduction of shadows under the eyes. Fibrin PRF is frequently used for filling the nasolabial lines and lifting the corners of the mouth. Visualization ©

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Platelet-Rich Fibrin London — Fibrin Is Similar to Platelet-Rich Plasma

Platelet-Rich Fibrin — Indications and Effects After the Treatment

Platelet-rich fibrin treatment was created for people who no longer want to use dermal fillers and hyaluronic acid but expect natural and safe skin regeneration and reconstruction of the lost face volume.

The indications for the treatment are signs of skin ageing:

  • wrinkles (smoker’s wrinkles, crow’s feet, horizontal wrinkles on the forehead, Venus rings on the neck)
  • facial furrows (marionette furrows, nasolabial furrows)
  • skin laxity
  • loss of volume and firmness of the skin, not only on the cheeks or under the eyes
  • tear troughs and dark circles under the eyes

The combination of plasma and fibrin ensures long-term treatment effects:

  • improvement of skin tension
  • deep moisturising and regeneration of the skin
  • reduction of discoloration
  • smoothing out visible wrinkles
  • treatment of poorly healing wounds (in the case of diabetes, bone reconstruction, and periodontal disease treatment)
  • treatment of alopecia and hair loss
  • reducing dark circles and shadows under the eyes
  • improvement of blood supply to the treatment area
  • removal of acne scars
  • removing stretch marks
  • change in face volumetry

Platelet-Rich Fibrin London and Birmingham — What Does the Procedure Look Like?

A few days before the procedure, do not use drugs that reduce blood clotting, e.g., aspirin, acetylsalicylic acid, ketoprofen, diclofenac, naproxen, indomethacin, ibuprofen, piroxicam.

Platelet-rich fibrin treatment at Eskulap London and Birmingham consists of several steps.

  1. At the beginning, blood is taken from the patient — about 8-16 ml.
  2. The blood is then prepared under suitable conditions to obtain fibrin. This allows us to obtain a preparation consisting of a cross-linked three-dimensional structure of fibrin fibres and a large number of platelets and growth factors.
  3. In the final phase, we apply the preparation to the patient. We can use platelet-rich fibrin as a filler, a safe alternative to hyaluronic acid, or a mesotherapy to renormalise the skin.

The entire process may take up to an hour. It is characterised by high safety because 100% of the material comes from the patient’s own blood, so there is no risk of allergies or inflammatory complications.

After the procedure, some patients may have slight redness at the injection site, which disappears on its own after a few hours. Thanks to the applied anaesthetic cream and the small size of the needle, the procedure is practically painless. For best results, we recommend repeating the treatment 3 to 5 times every 3 to 4 weeks. Then, we recommend a maintenance treatment every 3 to 6 months.

Lifting the Volume of Delicate Skin Not Only Under the Eyes Is an Advantage of Platelet-Rich Fibrin

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    Platelet-Rich Fibrin London and Birmingham — Who Is PRF Fibrin Recommended For?

    Platelet-rich plasma and fibrin are very widely used in aesthetic medicine. They are mainly used in regenerative procedures that nourish the skin. At Eskulap Clinic in London, we use plasma and fibrin in situations where the skin needs filling, moisturising, evening out skin tone and hyperpigmentation, and smoothing wrinkles and pores. These treatments are also a proven solution for patients who do not want to undergo treatments with dermal fillers. The same goes for patients who are allergic or are concerned about complications after hyaluronic acid treatments.

    Unlike dermal fillers, fibrin is safe and does not cause venous or arterial embolism. The effect is immediate, thanks to the volumising scaffolding made of fibrin fibres under the skin. Platelet-rich fibrin is an excellent method of improving the appearance of the face, removing wrinkles, filling nasolabial furrows, or improving the appearance of the delicate eye area. It also works well for treatments of the neck and hands. We use fibrin and plasma to reduce hair loss or reduce scars and stretch marks, not to mention skin lifting and firming treatments. Using active fibrin in parallel with other treatments, such as a CO2 laser or Dermapen, will bring additional results.

    Who Shouldn’t Undergo Platelet-Rich Fibrin Treatment?

    Treatments for pregnant and breastfeeding women are not recommended. Various diseases, especially chronic and severe ones, are also contraindications. These include, for example, diabetes mellitus, severe chronic cardiovascular disease, and active inflammation.

    The list also includes:

    • blood diseases
    • cancer
    • skin inflammation
    • active herpes
    • treatment with anticoagulants
    • taking aspirin
    • diabetes (unregulated)
    • acute autoimmune diseases
    • chronic liver disease
    • hepatorenal syndrome
    • patients treated with immunosuppressants
    • acute viral infection (HCV, HBS, HIV)
    • systemic diseases: scleroderma, immune vascular diseases
    • nucleotide allergies
    • blood diseases associated with disturbances in the function or number of platelets and blood clotting
    • sepsis
    • other active skin infections
    • injection intolerance

    Aesthetic Medicine Skin Clinic in London and Birmingham office

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    What Is the Price of the Platelet-Rich Fibrin or PRF Treatment?

    PRF treatment is usually more expensive than plasma PRP treatment. The price is higher because treatment is more demanding, the ampoule to obtain fibrin is more expensive, and less material is obtained. However, we can offer PRF fibrin at the same price as PRP.

    Quality and Safety

    At Eskulap Clinic, each treatment is preceded by a consultation — we will recommend the right product, especially for your needs. Only qualified staff with medical education should perform treatments in the field of aesthetic medicine. Products used at the Aesthetic Medicine Skin Clinic are sourced from official distributors. Consultation before the procedure will dispel all your doubts and fears.

    Platelet Rich Fibrin - Before and After


    What is Platelet-Rich Fibrin (PRF), and how does it work for rejuvenation?

    Platelet-Rich Fibrin (PRF) is a natural substance derived from your blood that is rich in platelets and white blood cells. When injected into the skin, PRF stimulates collagen production, helping to rejuvenate and revitalise the skin.

    PRF injections can promote hair growth by boosting blood flow to the hair follicles and stimulating the production of new hair cells.

    PRF treatments in London can tighten loose skin, improve skin texture, and add volume to areas that show the first signs of ageing, resulting in a more youthful appearance.

    PRF (Platelet-Rich Fibrin) has a higher concentration of platelets and white blood cells compared to PRP (Platelet-Rich Plasma). PRF is spun at a lower speed during preparation, resulting in a final product that can tighten loose skin and add volume back to the skin.

    During a PRF treatment, a sample of your blood is collected and centrifuged to separate the platelet-rich fibrin. The PRF is then injected into the skin under the eyes or other targeted areas to rejuvenate and revitalise the skin.

    Yes, PRF injections can tighten loose skin and add volume to areas that may have lost firmness due to ageing or other factors.

    PRF is a safe and natural treatment since it uses your blood components. However, some individuals may experience mild swelling or redness at the injection site, which usually subsides within a few days.

    Contact data

    147 Ruislip Road,
    Greenford, London
    UB6 9QQ

    Shakespear Crescent
    Hockley, Birmingham
    B18 5BT

    phone 07747 474755

    Opening hours:

    Mon – Sat 11:00 – 18:00

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