Powdered Collagen Peptides Supplementation.


See how Collagen Supplementation works.

The word collagen derives from the Greek kolla, meaning “glue” and the suffix –gen, “producing”. The term accurately characterizes the action of this protein within the structural matrix of the skin and organs.

At Eskulap Aesthetic Medicine Clinic in London and Birmingham, collagen provides a structural matrix for various parts of the body such as connective tissue, cartilage, ligaments, tendons, bones, and teeth. It is insoluble in water and easily biodegradable and/or digestible in contact with acids or bases. There are more than 28 distinct types of collagen, with collagen types I, II and III making up the greatest portion (80-90%).
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077 4747 4755

Collagen is a protein.

Collagen Peptides

The mechanism of action of type I collagen is currently the subject of renewed interest thanks to the discovery of new molecular mechanisms involved in homeostasis of the ECM. The most recent findings regarding the ECM highlight the importance of molecular analysis in understanding the mechanisms ensuring homeostasis and the alterations occurring in fibrotic processes.

Nithya is composed of heterologous type I collagen microparticles. A proprietary extraction technology produces a collagen with biomimetic properties that simulate polymerized collagen breakdown and thus stimulate fibroblast clustering and the deposition of procollagen and, as a consequence, type IV endogenous collagen.
At the Aesthetic Medicine Clinic Eskulap mmKisiel London Birmingham and Słupsk, collagen therapy regenerates and rebuilds the skin, thus restoring its past resilience and natural glow.

Collagen: mechanism of action.

The production process does not alter the protein’s native structure and involves no chemical cross-linking: Nithya collagen thus maintains its native triple – helix, microfibrillar structure and the sequence of its polypeptide chain. This is the reason for its antigenic properties, eliminating the need for preliminary allergological tests.

Starting from the premise that normal skin has an overall negative ionic charge while the cellular membranes in aging skin has a greater positive ionic charge, the process of micronization – producing biomimetic collagen microfibrils – improves the hydrophyllic properties of type I collagen, giving a negative charge to the molecule. Thus charged, the collagen binds with tissue and remains bound longer, thus optimizing the disaggregation process of its triple helix structure. Type I collagen binds to and exerts traction on type IV collagen fibrils on the surface of the fibroblast membrane, transducing this mechanical action into the production of new ECM (mechanotransduction).

The type I collagen binds to type IV collagen in the ECM, giving rise to the process of mechanotransduction.

Dermal-connective bioregeneration.

The goal of this process is structural regeneration via both physiological reaction and a sufficient chemical/mechanical stimulation to trigger a regenerative reaction without leading to chronic or granulomatous inflammation, both supporting and relaxing the skin. Type I collagen exerts a mechanical action on the fibroblasts, which are thus stimulated to produce new ECM and thus new collagen, elastin, and endogenous glucosaminoglycans. This process, by means of which the cells regulate the mechanical properties of their environment, converts mechanical impulses into biochemical signals and thus leads to deposition, rearrangement or removal of the matrix, with the goal of maintaining form and function.

Hence, the ultimate goal of the complex cell-matrix-cell interconnections in connective tissue is to develop and maintain homeostasis in order to promote and prolong structural and functional integrity of tissue. This is why we speak of dermal-connective bioregeneration. The action of Nithya collagen faithfully reproduces the physiological process of regeneration of the ECM, creating the necessary preconditions for restoring wellness.

Injections with the use of Collagen - Reducing the signs of skin aging.

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077 4747 4755

Collagen protocol – face.

Injectable Nithya is available in packages of three 70-mg vials. Indications For treating chrono- and photoaging of face, neck and hands. For the regeneration of dermal and subdermal connective tissue via stimulation of fibroblasts and neocollagenesis . For remodelling genetic deformations, such as dermal hypotrophy and hypotonia, and compromised skin elasticity.

Frequency of treatment.

Every 15-20 days from the first administration for a total of 30 days. The protocol is geared to cell regenerative turnover, which is characterized by an average cycle of 14-15 days, and thus it is very important to observe the treatment timeline to ensure a constant cell regeneration rate. A recall dose should be administered one month after the end of the protocol, and the treatment cycle should be repeated 3-6 months later depending on physician’s judgement and results.

Nithya protocol – body.

Indications For treating cellulite, scars, stretch marks, sagging following aesthetic surgery such as liposuction. Nithya BODY is also indicated for treating body blemishes arising from chronoaging.

Frequency of treatment At least three treatments at three-week intervals with a recall dose one month later, depending on objective, condition of the patient, and clinical assessment.

For firming and hydrating all skin types. It is ideal follow up to aesthetic surgery such as liposuction, tummy tuck, or body sculpting after the skin has healed.


Type I heterologous collagen: injectable suspension + topical mousse -> Overall treatment (outpatient and home)
• Reduction in principal aging parameters of the face (wrinkles around eyes, loss of skin volume, nasolabial folds);
• 3D photo documentation with volumetric assessment and profilometry of skin around eyes support the outcomes of clinical tests:
• Improves skin tone
• Improves skin fullness
• Improves skin volume


Aesthetic Medicine Skin Clinic in London and Birmingham office

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Quality and Safety

Products used at the Aesthetic Medicine Skin Clinic Eskulap in west London and Birmingham office are prescription only drugs and available only to doctors. Consultation before the procedure will dispel all your doubts and fears.

Collagen - Before and After

Contact data

147 Ruislip Road,
Greenford, London

Shakespear Crescent
Hockley, Birmingham
B18 5BT

phone 07747 474755

Opening hours:

Mon – Sat 11:00 – 18:00

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